Locomotor trade-offs in mice selectively bred for high voluntary wheel running
نویسندگان
چکیده
منابع مشابه
Locomotor trade-offs in mice selectively bred for high voluntary wheel running.
We investigated sprint performance and running economy of a unique ;mini-muscle' phenotype that evolved in response to selection for high voluntary wheel running in laboratory mice (Mus domesticus). Mice from four replicate selected (S) lines run nearly three times as far per day as four control lines. The mini-muscle phenotype, resulting from an initially rare autosomal recessive allele, has b...
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Locomotion is central to behavior and intrinsic to many fitness-critical activities (e.g., migration, foraging), and it competes with other life-history components for energy. However, detailed analyses of how changes in locomotor activity and running behavior affect energy budgets are scarce. We quantified these effects in four replicate lines of house mice that have been selectively bred for ...
متن کاملOpen-field behavior of house mice selectively bred for high voluntary wheel-running.
Open-field behavioral assays are commonly used to test both locomotor activity and emotionality in rodents. We performed open-field tests on house mice (Mus domesticus) from four replicate lines genetically selected for high voluntary wheel-running for 22 generations and from four replicate random-bred control lines. Individual mice were recorded by video camera for 3 min in a 1-m2 open-field a...
متن کاملEndurance capacity of mice selectively bred for high voluntary wheel running.
Mice from four lines bred for high voluntary wheel activity run approximately 3-fold more revolutions per day and have elevated maximal oxygen consumption during forced treadmill exercise, as compared with four unselected control (C) lines. We hypothesized that these high runner (HR) lines would have greater treadmill endurance-running capacity. Ninety-six mice from generation 49 were familiari...
متن کاملBaseline and stress-induced plasma corticosterone concentrations of mice selectively bred for high voluntary wheel running.
The hypothalamic-pituitary-adrenal (HPA) axis is important in regulating energy metabolism and in mediating responses to stressors, including increasing energy availability during physical exercise. In addition, glucocorticoids act directly on the central nervous system and influence behavior, including locomotor activity. To explore potential changes in the HPA axis as animals evolve higher vo...
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ژورنال
عنوان ژورنال: Journal of Experimental Biology
سال: 2009
ISSN: 1477-9145,0022-0949
DOI: 10.1242/jeb.029058